epiya motiefs of caga and upper gastrointestinal diseases
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منابع مشابه
EPIYA motiefs of cagA and upper gastrointestinal diseases
EPIYA motiefs of cagA and upper gastrointestinal diseases Saeed Soleiman-Meigooni, Kaveh Baghaei, Abbas Yadegar, Samaneh Alizadeh Infectious Diseases Research Center, University of Medical Sciences, Tehran, Iran Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran 3Shahid Beh...
متن کاملDifferent distribution of Helicobacter pylori EPIYA- cagA motifs and dupA genes in the upper gastrointestinal diseases and correlation with clinical outcomes in iranian patients
AIM Our aim was to determine the EPIYA-cagA Phosphorylation sites and dupA gene in H. pylori isolates among patients with upper gastrointestinal diseases. BACKGROUND Pathogenicity of the cagA-positive Helicobacter pylori is associated with EPIYA motifs and higher number of EPIYA-C segments is a risk factor of gastric cancer, while duodenal ulcer-promoting gene (dupA) is determined as a protec...
متن کاملdifferent distribution of helicobacter pylori epiya- caga motifs and dupa genes in the upper gastrointestinal diseases and correlation with clinical outcomes in iranian patients
abstractbackground: pathogenicity ofthe helicobacter pylori-caga positive was associated with epiyamotifs and higher number of epiya-c segments is a risk for gastric cancer,while duodenal ulcer-promoting gene (dupa) is determinedas a protective factor against gastric cancer. our aim was to determine the epiya-cagaphosphorylation sites and dupa gene in h. pylori isolates amongpatients with upper...
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Virulence factors of Helicobacter pylori can predict the development of different gastroduodenal diseases. There are scarce reports in Cuba about H. pylori isolates genotyping. The aim of the present investigation was to identify allelic variation of the virulence genes vacA, cagA, and iceA in sixty-eight patients diagnosed as H. pylori positive by culture. In seven out of 68 patients, strains ...
متن کاملHelicobacter pylori vacA and cagA genotypes in patients from northeastern Brazil with upper gastrointestinal diseases.
Helicobacter pylori causes chronic gastric inflammation and significantly increases the risk of duodenal and gastric ulcer disease and distal gastric carcinoma. In this study, we evaluated the Helicobacter pylori vacA and cagA genotypes in patients from a Brazilian region where there is a high prevalence of gastric cancer. Polymerase chain reaction (PCR) was used to investigate vacA mosaicism a...
متن کاملprevalence of helicobacter pylori vaca, caga, cage, icea, baba2, and oipa genotypes in patients with upper gastrointestinal diseases.
helicobacter pylori has been strongly associated with peptic ulcer diseases, chronic gastritis, ulcers, and reported as a risk factor for gastric cancer, too. the vaculating cytotoxin (vaca), the cytotoxin associated genes (caga), the induced by contact with epithelium factor antigen (icea gene), blood adhesion binding antigen (baba2), and outer membrane protein oipa have been described as diff...
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عنوان ژورنال:
gastroenterology and hepatology from bed to benchجلد ۸، شماره ۳، صفحات ۲۰۱۵-۸
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